A quantitative study of folic acid requirements and reversal of aminopterin inhibition in drosophila.
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چکیده
705 706 708 Reversal of p-Aminobenzoic Acid Inhibition of Growth of Rickettsiae by p-Hydroxybenzoic Acid in Agar-Slant Tissue Culture: N. Takemori and M. Kitaoka . 710 On the Presence of the Triphosphothiamine (TPT) in the Liver: A. Rossi-Fanelli, N. Siliprandi, and P. Fasella . _.711 Comments and Communications Ernest G. Beinhart, H. A. Cole, and Ben Stern .............. 713 Operations Diagnosis in Research
منابع مشابه
A Study of the Relation between Folic Acid and Tissue Ascorbic Acid* by Morton
Many instances of a close relationship between folic acid and ascorbic acid have been reported in the literature. Johnson and Dana (1) have shown that ascorbic acid relieves many of the abnormalities noted in a folic acid deficiency syndrome. Woodruff and Darby (2) have reported that folic acid aids in correcting the abnormal tyrosine metabolism of the scorbutic guinea pig. Nichol and Welch (3,...
متن کاملInhibition of nucleic acid synthesis by folic acid antagonists.
Woolley and Pringle (13) have recently reported the formation of 4-amino-5-carboxamidoimidazole during growth of Escherichia coli in the presence of 4-aminopteroylglutainic acid (aminopterin). Some of us have observed that excessive doses of folie acid speed up the leukemic process in mice and that folie acid will reverse the well known antileukemic action of aminopterin (11). This reversal of ...
متن کاملA study of the relation between folic acid and tissue ascorbic acid.
Many instances of a close relationship between folic acid and ascorbic acid have been reported in the literature. Johnson and Dana (1) have shown that ascorbic acid relieves many of the abnormalities noted in a folic acid deficiency syndrome. Woodruff and Darby (2) have reported that folic acid aids in correcting the abnormal tyrosine metabolism of the scorbutic guinea pig. Nichol and Welch (3,...
متن کاملInhibition of Drought Stress Using Folic Acid in Kentucky bluegrass (Poa pratensis L.) under in vitro culture
Considering the high water requirement of grass during growth stages and the limitation of irrigation sources, it is important to find a suitable way to reduce the water requirement of the lawns as cover plants used in the Landscape. The purpose of this study was to investigate the effect of 2,4,5-T on the induction of callus from the hypocotyl explant in Kentucky bluegrass, induce in vitro dro...
متن کاملThe Effect of 4-amino-pteroylglutamic Acid (aminopterin) on Human Leukemic Leukocytes in Vitro
S EEGERS et synthesized N-[4[(2.,4-diamino-6-pteridyl)-methyl]-amino benzoyl]-glutamic acid, (4-amino-pteroylglutamic acid, or Aminopterin), as a potential antagonist to folic acid, and found it inhibited the growth of S. faecalis R. in low concentrations, the inhibition being reversible by means of folic acid. Subsequently, slowing of growth and depression of the red and white blood cell count...
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عنوان ژورنال:
- Science
دوره 116 3026 شماره
صفحات -
تاریخ انتشار 1952